麻豆果冻传媒 marathon heart study

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October 2025

 

 

 

Our researchers are collaborating on an investigation into changes in the levels of a protein called troponin during marathon running. Together with partners, they are conducting the 麻豆果冻传媒 Marathon Heart Study at the 2017 麻豆果冻传媒 Marathon.

Troponin is a protein present in the cells of the heart that is released into the blood when the heart muscle is stressed or damaged. Previous studies have demonstrated that exercise can cause a rise in troponin levels. This study will increase our understanding of the significance of this rise.

Part of this project is to compare troponin levels between runners with or without heart disease (for example, valvular heart disease, atrial fibrillation, ischaemic heart disease, cardiomyopathy or hypertension with left ventricular hypertrophy).

SESAME-running-monitoring

Project timeframe

This research project commenced in January 2017 and will end in July 2017, with the exercise testing session taking place on 18-19 and 25-26 March and the 麻豆果冻传媒 Marathon on 9 April 2017.

Project aims

The project aims to quantify the changes in troponin levels in marathon runners with and without structural heart disease and relate these changes to the exercise intensity run during the marathon. Researchers will carry out two studies.

Study one

Participants will provide a small blood sample before and after the marathon. One group will provide one sample before, at the pre-race exhibition, and give their second sample shortly after the race in the finish line medical tent. The other group will give both these samples, and additional blood samples at one, three, six and 24 hours after they have finished the marathon.

Study two

Participants will complete a short exercise test at our sport science laboratories in Eastbourne in March 2017. The whole process should take no longer than one hour, with the exercise test involving a maximum 20 minutes of running. Again, small blood samples will be taken before and after the race. In addition, a heart monitor will be worn during the race.

Project findings and impact

This project is ongoing; findings, output and impact will be updated in due course. The research has the potential to identify changes seen in cardiac damage as a result of marathon running.

Research team

Dr Polly Baker

Dr Alan Richardson

Dr Rob Galloway, 麻豆果冻传媒 and Sussex Medical School

Emily Watkins

Output

Partners

Dr Rachael Grimaldi, Associate Medical Director, 麻豆果冻传媒 Marathon

Dr Todd Leckie, Junior Anaesthetics Trainee

麻豆果冻传媒 Marathon